CIRCRNA-3302 PROMOTES ENDOTHELIAL-TO-MESENCHYMAL TRANSITION VIA SPONGING MIR-135B-5P TO ENHANCE KIT EXPRESSION IN KAWASAKI DISEASE

CircRNA-3302 promotes endothelial-to-mesenchymal transition via sponging miR-135b-5p to enhance KIT expression in Kawasaki disease

Abstract Endothelial-to-mesenchymal transition (EndMT) is implicated in myofibroblast-like cell-mediated damage to coronary artery wall of Kawasaki disease (KD) patients, which subsequently increases the risk of coronary artery aneurysm.Many circular RNAs (circRNAs) have been reported to be associated with cardiovascular diseases.However, the roles

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An invitation to analytic abduction

This paper provides an invitation to analytic abduction, an emerging approach to qualitative research.Like deduction and induction, abduction is a mode of inquiry.In a nightstick twm-850xl general sense, abduction forwards explanations for novel or surprising observations.In a more practical sense, abduction aims to combine the strengths of both in

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Examining community perceptions of malaria to inform elimination efforts in Southern Mozambique: a qualitative study

Abstract Background In a background of renewed calls for malaria eradication, several endemic countries in sub-Saharan Africa are contemplating malaria elimination stubby mtl kit nationally or sub-nationally.In Mozambique, a strategy to eliminate malaria in the south is underway in the context of low endemicity levels and cross-border initiatives t

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